Clustered Expression Profiles
نویسندگان
چکیده
M. Fellenberg, S. Stocker, M. Münsterkötter, H.W. Mewes http://www.mips.biochem.mpg.de/proj/expression/ 1 Experiment Portal – Features of each Clustering. The entry point of the web pages presents a list of the analyzed experiments. For a selected experiment the Experiment Portal provides the parameters that are used for the clustering and a histogram of cluster sizes. A valid clustering shows an approximate Poisson distribution of cluster sizes.
منابع مشابه
Microarray Time-Series Data Clustering via Multiple Alignment of Gene Expression Profiles
Genes with similar expression profiles are expected to be functionally related or co-regulated. In this direction, clustering microarray time-series data via pairwise alignment of piece-wise linear profiles has been recently introduced. We propose a k-means clustering approach based on a multiple alignment of natural cubic spline representations of gene expression profiles. The multiple alignme...
متن کاملEST databases as multi-conditional gene expression datasets.
Large-scale expression data, such as that generated by hybridization to microarrays, is potentially a rich source of information on gene function and regulation. By clustering genes according to their expression profiles, groups of genes involved in the same pathways or sharing common regulatory mechanisms may be identified. Publicly-available EST collections are a largely unexplored source of ...
متن کاملPCluster: Probabilistic Agglomerative Clustering of Gene Expression Profiles
A central problem in analysis of gene expression data is clustering of genes with similar expression profiles. In this paper, I describe an hierarchical clustering procedure that is based on simple probabilistic model. This procedure clusters genes with respect to a target classification of conditions, so that genes that are expressed similarly in each group of conditions are clustered together.
متن کاملApplication of Singular Value Decomposition and Functional Clustering to Analyzing Gene Expression Profiles of Renal Cell Carcinoma
Microarray gene expression profiles of both renal cell carcinoma (RCC) tissues and a RCC cell line were analyzed using singular value decomposition (SVD) and functional clustering. The SVD projections of the expression profiles revealed significant differences between the profiles of RCC tissues and a RCC cell line. Based on the biological processes, selected genes were annotated and clustered ...
متن کاملTime Series Analysis of Gene Expression and Location Data
We develop a method for integrating time series expression profiles and factor-gene binding data to quantify dynamic aspects of gene regulation. We estimate latencies for transcription activation by explaining time correlations between gene expression profiles through available factorgene binding information. The resulting aligned expression profiles are subsequently clustered and again combine...
متن کاملCharacterization of Gene Functional Expression Profiles of Plasmodium Falciparum
ABSTRACT Our objective was to provide functional characterization of gene expression related to Intraerythrocytic Developmental Cycle (IDC) of Plasmodium Falciparum. We explored a hypothesis that genes with same or similar function are likely to have similar expression profiles. Analysis of 1,051 Gene Ontology (GO) terms represented by at least two genes in Plasmodium Falciparum microarray data...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2000